<>  All Triptans, Ergotamine family drugs are dangerous drugs because they are vasoconstrictors factors. What does that mean? That mean they do the diameter of vessels too much smaller. What does that mean? That mean less blood go through this vessels. What does that mean? That mean less blood to the irrigated  area. What does that mean? That mean less blood to the heart muscles. What does that mean? That mean the heart cant work in full power. What does that mean? That mean he can work at the lowest power because the blood that supply heart muscles to work is in too low value. But I have to go to the stadium to play a football match! You cant go to play, because when you do effort your heart muscle need more blood, but your heart cant get it because you took triptans drugs. What can happen if I play? The heart response to the less blood when he need more is known, it’s an ischemic syndrome, that chest pain will be the first alarm. Yes I read in the enclosed instruction in the triptans box that when patients feel chest pain he must stop taken it! Yes they recognize that heart problems can occur due to this drugs. Why they do it when they know that it can be dangerous for heart? Always there are fools!!!!! Why doctors make me take it? Also there are much than fools!!!!!! When they meet tog ethers always disasters happen as Jim Cary movie
All medicaments that work as Vasoconstrictors are dangerous drugs, for some patients even in small quantity they are dangerous,,,,. Why??Migraine has 2 stage:1- Aura stage.2- Headaches stage.What happen in Aura?In aura stage, a special alarm system for migraine will be started. This alarm system will work due to a strong vasoconstrictors in small arteries into the brain in a certain zone. So if this zone is visual zone as most migraine patients then aura symptoms will be visual.In some migraine cases aura will be absent.What happen in headaches stage?In this stage, a strong vasodilatation of certain extra cranial artery will happen, that cause headache itself, while at the same time intra cranial arteries will have strong vasoconstrictions.Extra cranial vasodilatation will cause headaches, while intracranial vasoconstrictions will cause all accompanied symptoms related to the affected intracranial area.This intra cranial affected area explain the different form of migraine headaches.Intra cranial strong vasoconstriction in some migraine patients, can explain the small brain ischemic modification that we see in MRI of brain in some migraine patients.That explain why triptans and ergotamine can be as a poison for migraine patients.They can help to reduce headache itself by forced this vasodilatation to be smaller, but at the same time it forced the constricted vessels to be much smaller.You can imagine the real danger here, especially in BAM.
Triptan-Antidepressant Interaction Causing Serotonin Syndrome Triptan-Antidepressant Interaction Causing Serotonin Syndrome FDA Public Health Advisory On July 19, 2006, the FDA issued a Public Health Advisory warning of the potential danger associated with the use of 5-hydroxytryptamine agonists (triptans) in patients who are also taking selective serotonin reuptake inhibitors (SSRIs) and selective serotonin/norepinephrine reuptake inhibitors (SNRIs). http://www.fda.gov/cder/drug/advisory/SSRI_SS200607.htm http://www.pswi.org/irx/triptan.htm